Generation of a human iPSC line from a patient with a defect of intergenomic communication
| dc.contributor.author | Zurita-Díaz, Francisco | |
| dc.contributor.author | Galera-Monge, Teresa | |
| dc.contributor.author | González-Páramos, Cristina | |
| dc.contributor.author | Moreno-Izquierdo, Ana | |
| dc.contributor.author | Schneiderat, Peter | |
| dc.contributor.author | Fraga, Mario F. | |
| dc.contributor.author | Fernández, Agustin F. | |
| dc.contributor.author | Garesse, Rafael | |
| dc.contributor.author | Gallardo, M. Esther | |
| dc.date.accessioned | 2026-02-05T13:55:33Z | |
| dc.date.available | 2026-02-05T13:55:33Z | |
| dc.date.issued | 2016-01-10 | |
| dc.identifier.citation | Zurita, F., Galera, T., González-Páramos, C., Moreno-Izquierdo, A., Schneiderat, P., Fraga, M. F., Fernández, A. F., Garesse, R., & Gallardo, M. E. (2015). Generation of a human iPSC line from a patient with a defect of intergenomic communication. Stem Cell Research, 16(1), 120-123. https://doi.org/10.1016/j.scr.2015.12.016 | es |
| dc.identifier.issn | 1873-5061 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12412/7081 | |
| dc.description.abstract | Human iPSC line PG64SV.2 was generated from fibroblasts of a patient with a defect of intergenomic communication. This patient harbored a homozygous mutation (c.2243G>C; p.Trp748Ser) in the gene encoding the catalytic subunit of the mitochondrial DNA polymerase gamma gene (POLG). Reprogramming factors Oct3/4, Sox2, Klf4, and cMyc were delivered using a non integrative methodology that involves the use of Sendai virus. | es |
| dc.language.iso | eng | es |
| dc.title | Generation of a human iPSC line from a patient with a defect of intergenomic communication | es |
| dc.type | article | es |
| dc.identifier.doi | 10.1016/j.scr.2015.12.016 | |
| dc.journal.title | Stem Cell Research | es |
| dc.page.initial | 120 | es |
| dc.page.final | 123 | es |
| dc.rights.accessRights | openAccess | es |
| dc.volume.number | 16 | es |